SMTPSenderRefused-4.4.2 Message submission rate for this client has exceeded the configured limit

I am troubling to fix these issue, can anyone please help me to fix these issues?
I’ve have three email accounts in which one is working fine and another two are throwing these errors:

Email Server: Exchange Server 2013
Error 1:

Traceback (most recent call last):
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/app.py", line 60, in application
    response = frappe.api.handle()
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/api.py", line 55, in handle
    return frappe.handler.handle()
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/handler.py", line 22, in handle
    data = execute_cmd(cmd)
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/handler.py", line 61, in execute_cmd
    return frappe.call(method, **frappe.form_dict)
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/__init__.py", line 1042, in call
    return fn(*args, **newargs)
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/email/doctype/email_queue/email_queue.py", line 45, in send_now
    send_one(name, now=True)
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/email/queue.py", line 478, in send_one
    raise e
  File "/home/erpadmin/frappe-bench/apps/frappe/frappe/email/queue.py", line 417, in send_one
    smtpserver.sess.sendmail(email.sender, recipient.recipient, message)
  File "/usr/lib/python3.7/smtplib.py", line 867, in sendmail
    raise SMTPSenderRefused(code, resp, from_addr)
smtplib.SMTPSenderRefused: (421, b'4.4.2 Message submission rate for this client has exceeded the configured limit', 'Email Account Name <email-address>')

Error 2:

smtplib.SMTPDataError: (550, b'5.7.60 SMTP; Client does not have permissions to send as this sender')

Check your sending email address. It should be the same as the email address user in the account. Cheers

Thank you for your kind response but we have fixed this using:

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